Exploring intermediate phenotypes with EEG: Working memory dysfunction in schizophrenia
نویسندگان
چکیده
منابع مشابه
Exploring intermediate phenotypes with EEG: working memory dysfunction in schizophrenia.
This review brings together two strands of investigation in the neuropsychology and neurophysiology of schizophrenia that have been particularly productive over the last 20 years. We review the literature on working memory deficits, particularly in the visual domain, and changes in oscillatory neural activity as measured with electroencephalography (EEG) and magnetoencephalography (MEG). We arg...
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Objective: This study aimed to investigate the verbal memory and working memory impairment in healthy siblings of patients with schizophrenia. Methods: The purpose of this study was to compare cognitive deficits in siblings of the patients with schizophrenia and control group. A total of 35 unaffected siblings of patients with schizophrenia were selected from the relatives of the pat...
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OBJECTIVE This study tested the hypothesis that impaired working memory is a core deficit underlying multiple neuropsychological deficits in schizophrenia patients. METHOD The subjects were 27 men with stable chronic schizophrenia treated with atypical antipsychotics and 38 normal participants. They were assessed with a battery of neuropsychological tests. Verbal working memory was measured w...
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Studies aiming to identify susceptibility genes for schizophrenia and other complex psychiatric disorders are faced with the confounds of subjective clinical criteria, commonly occurring phenocopies, significant between-subject variability of candidate traits, and the likelihood of allelic and locus heterogeneity that has been shown to define the genetics of other complex human brain and somati...
متن کاملWorking Memory in Schizophrenia
Background: Working memory has been reported to be impaired in schizophrenia, but there are inconsistencies in the literature. Therefore, we undertook the current study with the objective of assessing both auditory and visuospatial working memory tasks in a sample of schizophrenia patients in comparison to normal controls, and its correlation with psychopathology. Method: The sample comprised o...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2011
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2010.08.045